Bangladesh had been set a target of 274 for the win but resumed on the third morning on 11 for three and were bowled out inside 55 minutes.
Temba Bavuma scored an unbeaten half-century as South Africa reached 233 for four at end of Day 1
The loss of Bavuma will further weaken their top six, especially as the experienced Reeza Hendricks has withdrawn from the squad after the birth of his first child, while the in-form Rassie van der Dussen is doubtful for the first match of the series, at least, with a grade one left quadriceps strain.
South Africa won their T20 series against world champions West Indies and Ireland, and will once again be captained by Temba Bavuma in both formats.
Jonny Bairstow led England to within 40 runs of South Africa's first innings total, with seven wickets in hand, on the first day of the second Test at Old Trafford on Thursday.
Seamer Lungi Ngidi showed all his guile to take five wickets for 19 runs as South Africa skittled West Indies for 97 and seized the initiative on the first day of the first Test in Saint Lucia on Thursday.
Wicketkeeper-batsman Quinton de Kock will be available for the ODI series after his abrupt retirement from Test cricket on Thursday, while all-rounder Dwaine Pretorius earns a recall.
South Africa in trouble at 58-4 in 'Boxing Day' Test
VIn a dramatic turn of events on Day 3, India faced a resounding defeat against South Africa in the first Test as their batting lineup crumbled, managing only 131 runs in the second innings after the hosts posted a formidable 408 in their initial essay.
Fast bowler Duanne Olivier has been recalled for South Africa's home Test series against India, a reward for excellent domestic form from a player who shot to prominence four years ago before taking up a Kolpak contract.
Opener Fakhar Zaman smashed his second century in as many matches as Pakistan beat a much-changed South Africa by 28 runs in the third and final One-Day International, in Pretoria on Wednesday, to clinch the series 2-1.
After fast bowler Khaled Ahmed (2-59) had South Africa opener Sarel Erwee (24) caught by wicketkeeper Litton Das, Taijul claimed the next three wickets.
Kagiso Rabada is a huge figure in the South African seam attack and his loss for the opening Test against England would be a massive blow as he battles back from an ankle problem.
South Africa continued their recent dominance of Australia in this format having won 11 of their last 12 ODI meetings dating back to 2016.
23 wickets and several records fell on the opening day of the second and final Test in Cape Town on Wednesday.
IMAGES from the first Test played between South Africa and India in Centurion on Tuesday
Images from Day 2 of the second Test between India and South Africa in Johannesburg on Tuesday.
Seamer Ollie Robinson took 5/49 as England skittled South Africa out for 118 on the third day of the third Test at The Oval on Saturday, before grinding their way to 154/7 in reply, a lead of 36 runs.
Matt Henry produced a career-best seven for 23 in a spectacular display of pace bowling as New Zealand skittled out South Africa for 95 in two sessions to take charge of the opening Test in Christchurch on Thursday.
South Africa lost two wickets after tea but extended their lead over New Zealand to 211 runs by the close of Day 3 to leave the second Test delicately poised, in Christchurch, on Sunday.
South Africa will be led by captain Quinton de Kock as they come off a 2-0 home series win over Sri Lanka that concluded on Tuesday.
World No 1 India may feel they have never had a better chance of winning their first ever Test series in South Africa.
Australia reduced South Africa to 149 for six at the close of play on the fourth day of the rain-disrupted third Test on Saturday after declaring on 475/4 in pursuit of a victory that would give them a 3-0 series sweep.
Australia completed a six-wicket victory within two days in the first Test against South Africa on Sunday as the Proteas crumbled on a green Gabba wicket that played straight into the home bowlers' hands.
Victory for England would see them take the series, which is poised at 1-1.
Victorious India will seek more of the same when the second Test against South Africa starts at The Wanderers on Monday, but for the home side there is much to ponder as they try to level the series at a ground where they have never beaten the visitors.
The selectors have added uncapped batsman Raynard van Tonder, seamer Lutho Sipamla and all-rounder Dwaine Pretorius to the squad.
Himachal Pradesh Cricket Association (HPCA) general manager Col HS Manhas said all precautions are being taken by the medical teams amid the coronavirus scare.
South Africa have recalled top-order batsmen Faf du Plessis and Rassie van der Dussen for their three-match One-Day International tour of India later this month, while left-arm spinner George Linde is named in the squad for the first time. The squad will be captained by Quinton de Kock and play the first ODI in Dharamsala in March 12.
A fiery spell from captain Ben Stokes dragged England back into the match but South Africa remained the happier side as they reached 289/7 at the close on the second day of the first Test at Lord's on Thursday.
India's three-match ODI campaign against South Africa starting on Thursday where the hosts would be aiming to put the 'New Zealand Nightmare' behind them.
Patidar or Rinku set for debut; India look to seal series
India's journey into their ODI future will hit its first stop during the opening match against South Africa on Sunday.
Meanwhile, South Africa have included uncapped off-spinner Prenelan Subrayen and seamer Lizaad Williams in their squad for the two-Test series in the West Indies that starts on June 10.
Led by Quinton de Kock, South Africa's 44 cricketers, who are part of a men's high performance squad, have returned to training amid the COVID-19 pandemic after getting approval from the country's sports ministry. South Africa has reported more than 1,38,000 COVID-19 cases with over 2,400 deaths.
IMAGES from Day 1 of the 1st Test played between England and South Africa at Lord's on Wednesday.
Jasprit Bumrah took 6/61 as India crushed South Africa by seven wickets to level the two-match series 1-1.
Images from Day 2 of the third Test between Australia and South Africa at the Sydney Cricket Ground on Thursday
Heinrich Klaasen smashed an unbeaten century as South Africa claimed a 74-run victory over Australia in their first one-dayer played on a slow Boland Park wicket on Saturday. After winning the toss, South Africa overcame an early wobble to post 291 for seven in their 50 overs, a total boosted by the maiden ODI ton from middle-order batsman Klaasen, who crashed 123 from 114 balls. Australia were up with the run-rate for much of their reply, but South Africa then strangled the scoring with intelligent use of the slow pitch as the visitors slumped to 217 all out from 45.1 overs.
A desperate India seek to restore parity against South Africa and remain consequential in the World Test Championship.